Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

PGF2b (Z)-7-[(1R,2S,3R,5R)-3,5- dihydroxy-2-[(E...

Synonyms: PGF2-beta, PGF2beta, SureCN3364356, BSPBio_001493, CHEBI:28922, ...

Kimball, F.A. et al., Eskay, R.L. et al., Gandolfi, C. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on PGF2beta

Prostaglandin E2 (PGE2), PGF2alpha, PGF2beta was infused into a lateral ventricle of the brain of adult male rats, after pretreatment with normal rabbit serum (NRS) or anti-LH-RH serum, and the concentration of LH in arterial plasma was determined [1].
Serum progesterone levels were unchanged 2 hours and 6 hours after treatment with 100 microgram PGF2beta and 2 hours after treatment with 1 mg PGF2beta [2].
Esterification with inversion is a highly stereospecific reaction by which one-step conversion of PGF2alpha to PGF2beta is obtained with very satisfactory yield [3].

Associations of PGF2beta with other chemical compounds

Progesterone levels were depressed to less than 1 ng/ml 6 hours after treatment with 1 mg PGF2beta [2].

References

Inhibition of prostaglandin-enhanced release of LH by antiserum to luteinizing hormone releasing hormone. Eskay, R.L., Warberg, J., Porter, J.C. Neuroendocrinology (1977) [Pubmed]
Effect of in vivo prostaglandin treatment on 3H-PGF2alpha uptake in hamster corpora lutea. Kimball, F.A., Porteus, S.E. Prostaglandins (1978) [Pubmed]
Prostaglandins X. An improved route for synthesis of PGF2beta analogues. Gandolfi, C., Fumagalli, A., Pellegata, R., Doria, G., Ceserani, R., Franceschini, J. Il Farmaco; edizione scientifica. (1976) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share