Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1NSVEA (3S,6aR,6aS,8aS,14bS)- 4,4,6a,6b,8a,11,14b...

Synonyms:

Baumann, D. et al., Della Loggia, R. et al., Zitterl-Eglseer, K. et al.

Zitterl-Eglseer, Reznicek, Jurenitsch, Novak, Zitterl, Franz,

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High impact information on Faradiol

The anti-inflammatory activity of different CO2 extracts is proportional to their content of faradiol monoester, which can be taken as a suitable parameter for the quality control of Calendula preparations [1].
The main compounds of lipophilic extracts of flower heads of marigold (Calendula officinalis L.) are triterpendiol esters, mainly faradiol laurate, faradiol myristate and faradiol palmitate [2].

Analytical, diagnostic and therapeutic context of Faradiol

The HPLC fingerprints of the extracts, the yields of total extract and the concentration of faradiol esters obtained with analytical and pilot scale extractors under the same conditions were comparable [3].
The effects of pressure and co-solvent on the extraction of anti-inflammatory faradiol esters in marigold (Calendula officinalis L.) were investigated by supercritical fluid extraction at laboratory and pilot scales [3].

References

The role of triterpenoids in the topical anti-inflammatory activity of Calendula officinalis flowers. Della Loggia, R., Tubaro, A., Sosa, S., Becker, H., Saar, S., Isaac, O. Planta Med. (1994) [Pubmed]
Morphogenetic variability of faradiol monoesters in marigold Calendula officinalis L. Zitterl-Eglseer, K., Reznicek, G., Jurenitsch, J., Novak, J., Zitterl, W., Franz, C. Phytochemical analysis : PCA. (2001) [Pubmed]
Supercritical carbon dioxide extraction of marigold at high pressures: comparison of analytical and pilot-scale extraction. Baumann, D., Adler, S., Griiner, S., Otto, F., Weinreich, B., Hamburger, M. Phytochemical analysis : PCA. (2004) [Pubmed]

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