Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL197165 methylN-[(1S)-1-[[benzyl- [(2S)-2-hydroxy...

Synonyms: SureCN3525453, CHEBI:40395, CHEBI:432094, AC1NS1MP, 2bqv, ...

Ohno, S., Preissner, K.T.

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Disease relevance of methyl N-[(1S)-1-[[benzyl-[(2S)-2-hydroxy-2-[[(1S,2R)-2-hydroxyindan-1-yl]carbamoyl]-3-phenyl-propyl]amino]carbamoyl]-2-methyl-propyl]carbamate

It was suggested that plasmid-encoded 6-amino hexanoic acid linear oligomer hydrolase that suddenly endowed Flavobacterium sp. K172 with the capacity to live off nylon by-products arose by the above mechanism [1].

High impact information on methyl N-[(1S)-1-[[benzyl-[(2S)-2-hydroxy-2-[[(1S,2R)-2-hydroxyindan-1-yl]carbamoyl]-3-phenyl-propyl]amino]carbamoyl]-2-methyl-propyl]carbamate

Heparin only moderately interfered with the vitronectin-plasminogen interaction, whereas high concentrations of 6-amino-hexanoic acid inhibited binding [2].

References

Segmental homology and internal repetitiousness identified in putative nucleic acid polymerase and human hepatitis B surface antigen of human hepatitis B virus. Ohno, S. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
Specific binding of plasminogen to vitronectin. Evidence for a modulatory role of vitronectin on fibrin(ogen)-induced plasmin formation by tissue plasminogen activator. Preissner, K.T. Biochem. Biophys. Res. Commun. (1990) [Pubmed]

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