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Chemical Compound Review:

HOPDA (3E,5E)-6-hydroxy-2-oxo-6- phenyl-hexa-3,5...

Synonyms: AC1NUSYI, CHEBI:17820, 2-Hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid

Furukawa, K. et al., Kim, E. et al., Ohtsubo, Y. et al.

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Disease relevance of CHEBI:17820

The cloned bphA, bphB and bphC genes of Pseudomonas pseudoalcaligenes KF707, coding for conversion of biphenyl into a ring meta-cleavage product (2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid), carried random insertions of Tn5-B21 [1].

High impact information on CHEBI:17820

Expression of the bph genes involved in biphenyl/PCB degradation in Pseudomonas sp. KKS102 induced by the biphenyl degradation intermediate, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid [2].
Genetic structures of the genes encoding 2,3-dihydroxybiphenyl 1,2-dioxygenase and 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase from biphenyl- and 4-chlorobiphenyl-degrading Pseudomonas sp. strain DJ-12 [3].

References

Gene-specific transposon mutagenesis of the biphenyl/polychlorinated biphenyl-degradation-controlling bph operon in soil bacteria. Furukawa, K., Hayashida, S., Taira, K. Gene (1991) [Pubmed]
Expression of the bph genes involved in biphenyl/PCB degradation in Pseudomonas sp. KKS102 induced by the biphenyl degradation intermediate, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid. Ohtsubo, Y., Nagata, Y., Kimbara, K., Takagi, M., Ohta, A. Gene (2000) [Pubmed]
Genetic structures of the genes encoding 2,3-dihydroxybiphenyl 1,2-dioxygenase and 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase from biphenyl- and 4-chlorobiphenyl-degrading Pseudomonas sp. strain DJ-12. Kim, E., Kim, Y., Kim, C.K. Appl. Environ. Microbiol. (1996) [Pubmed]

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