Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Ketocef (6R,7S)-3- (aminocarbonyloxymethyl)-7...

Synonyms: Cetroxil, Cefuril, Cefuroxim, Lifurox, Zinacef, ...

Bauhofer, A. et al.

Bauhofer, Celik, Plaul, Wulf, Torossian,

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Disease relevance of cefuroxime

OBJECTIVE: In a recently completed randomised clinical trial in patients with colorectal cancer resections the combination of the granulocyte-colony stimulating factor (G-CSF) + cefuroxime/ metronidazole (cef/met) was superior to ofloxacin/metronidazole (ofl/met) [1].

High impact information on cefuroxime

RESULTS: Survival rate was best in the G-CSF + cef/met group with 75% and was significantly improved compared to the cef/met placebo group, in which only 42% survived (P < 0.05) [1].

Gene context of cefuroxime

Survival rate between both G-CSF groups was similar being 75% in the cef/met and 72% in the ofl/met group [1].

References

Effects of G-CSF and antibiotic prophylaxis in a 2 x 2 factorial design on outcome in septic rats. Bauhofer, A., Celik, I., Plaul, U., Wulf, H., Torossian, A. Inflamm. Res. (2004) [Pubmed]

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