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Chemical Compound Review: 

Losec Sodium     sodium 5-methoxy-2-[(4-methoxy-3,5...

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Disease relevance of Esomeprazole

  • INTERVENTION: Endoscopically proven esophagitis (grades I-IV, Savary-Miller classification) was treated with omeprazole sodium, 40 mg/d (20 mg/d for children weighing <20 kg) as healing dose for 3 months, and 20 mg/d (10 mg/d for children weighing <20 kg) as maintenance dose for another 3 months [1].
  • Two hundred sixty-eight patients with GERD were recruited and randomly assigned to omeprazole sodium, 20 mg once daily, or ranitidine hydrochloride, 150 mg twice daily, for up to 6 months [2].

References

  1. Omeprazole: therapy of choice in intellectually disabled children. Böhmer, C.J., Niezen-de Boer, R.C., Klinkenberg-Knol, E.C., Meuwissen, S.G. Archives of pediatrics & adolescent medicine. (1998) [Pubmed]
  2. Effectiveness and costs of omeprazole vs ranitidine for treatment of symptomatic gastroesophageal reflux disease in primary care clinics in West Virginia. Kaplan-Machlis, B., Spiegler, G.E., Zodet, M.W., Revicki, D.A. Archives of family medicine. (2000) [Pubmed]
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