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Chemical Compound Review

Muriatic acid     chlorane

Synonyms: chlorum, Chlorowodor, Hydrochloride_, HCL], Bowl Cleaner, ...
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Disease relevance of hydrogen chloride


Psychiatry related information on hydrogen chloride


High impact information on hydrogen chloride


Chemical compound and disease context of hydrogen chloride


Biological context of hydrogen chloride


Anatomical context of hydrogen chloride


Associations of hydrogen chloride with other chemical compounds


Gene context of hydrogen chloride

  • Guanidine hydrochloride, and the overproduction of Ure2p 1-65 or Ure2-GFP have been shown to induce the elimination of [URE3] [36].
  • The same transient activation and subsequent inactivation of cyclin B1/Cdc2 kinase were observed after DNA damage by etoposide or bis-(2-chloroethyl)methylamine hydrochloride [37].
  • In addition, aromatase induction in MCF-7 cells could also be suppressed by PD153035 hydrochloride [38].
  • Since the inhibition of Ca2+ redistribution by an inhibitor of intracellular Ca2+ mobilization, 8-(diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride, inhibited TCR-induced FasL but not Fas, the expression of Fas appears to be independent of Ca2+ mobilization [39].
  • Through high capacity screening followed by chemical optimization, we identified a novel non-peptide CCR1 antagonist, R-N-[5-chloro-2-[2-[4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl ]-2-oxoethoxy]phenyl]urea hydrochloric acid salt (BX 471) [40].

Analytical, diagnostic and therapeutic context of hydrogen chloride


  1. Cocaine-induced coronary-artery vasoconstriction. Lange, R.A., Cigarroa, R.G., Yancy, C.W., Willard, J.E., Popma, J.J., Sills, M.N., McBride, W., Kim, A.S., Hillis, L.D. N. Engl. J. Med. (1989) [Pubmed]
  2. Impaired proximal duodenal mucosal bicarbonate secretion in patients with duodenal ulcer. Isenberg, J.I., Selling, J.A., Hogan, D.L., Koss, M.A. N. Engl. J. Med. (1987) [Pubmed]
  3. Fusion mutants of the influenza virus hemagglutinin glycoprotein. Daniels, R.S., Downie, J.C., Hay, A.J., Knossow, M., Skehel, J.J., Wang, M.L., Wiley, D.C. Cell (1985) [Pubmed]
  4. The toxicity and dose of desipramine hydrochloride. Amitai, Y., Frischer, H. JAMA (1994) [Pubmed]
  5. Evaluation of a new antihypertensive agent: prazosin hydrochloride (Minipress). Kosman, M.E. JAMA (1977) [Pubmed]
  6. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group. Knapp, M.J., Knopman, D.S., Solomon, P.R., Pendlebury, W.W., Davis, C.S., Gracon, S.I. JAMA (1994) [Pubmed]
  7. Magical thinking and imipramine poisoning in two school-age children. Herson, V.C., Schmitt, B.D., Rumack, B.H. JAMA (1979) [Pubmed]
  8. Recent advances in the pharmacotherapy of smoking. Hughes, J.R., Goldstein, M.G., Hurt, R.D., Shiffman, S. JAMA (1999) [Pubmed]
  9. Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial. Brady, K., Pearlstein, T., Asnis, G.M., Baker, D., Rothbaum, B., Sikes, C.R., Farfel, G.M. JAMA (2000) [Pubmed]
  10. Moderate- vs high-dose methadone in the treatment of opioid dependence: a randomized trial. Strain, E.C., Bigelow, G.E., Liebson, I.A., Stitzer, M.L. JAMA (1999) [Pubmed]
  11. Influenza virus M2 protein has ion channel activity. Pinto, L.H., Holsinger, L.J., Lamb, R.A. Cell (1992) [Pubmed]
  12. Effect of omeprazole and ranitidine on ulcer healing and relapse rates in patients with benign gastric ulcer. Walan, A., Bader, J.P., Classen, M., Lamers, C.B., Piper, D.W., Rutgersson, K., Eriksson, S. N. Engl. J. Med. (1989) [Pubmed]
  13. Effect of esophageal emptying and saliva on clearance of acid from the esophagus. Helm, J.F., Dodds, W.J., Pelc, L.R., Palmer, D.W., Hogan, W.J., Teeter, B.C. N. Engl. J. Med. (1984) [Pubmed]
  14. Reversal of morphine disruption of maternal behavior by concurrent treatment with the opiate antagonist naloxone. Bridges, R.S., Grimm, C.T. Science (1982) [Pubmed]
  15. Somatostatin cell processes as pathways for paracrine secretion. Larsson, L.I., Goltermann, N., de Magistris, L., Rehfeld, J.F., Schwartz, T.W. Science (1979) [Pubmed]
  16. Hyperthermia potentiates doxorubicin-related cardiotoxic effects. Kim, Y.D., Lees, D.E., Lake, C.R., Whang-Peng, J., Schuette, W., Smith, R., Bull, J. JAMA (1979) [Pubmed]
  17. Intrapleural tetracycline for the prevention of recurrent spontaneous pneumothorax. Results of a Department of Veterans Affairs cooperative study. Light, R.W., O'Hara, V.S., Moritz, T.E., McElhinney, A.J., Butz, R., Haakenson, C.M., Read, R.C., Sassoon, C.S., Eastridge, C.E., Berger, R. JAMA (1990) [Pubmed]
  18. Multiple extremity amputations in hypotensive patients treated with dopamine. Golbranson, F.L., Lurie, L., Vance, R.M., Vandell, R.F. JAMA (1980) [Pubmed]
  19. An assessment of diltiazem and hydrochlorothiazide in hypertension. Application of factorial trial design to a multicenter clinical trial of combination therapy. Burris, J.F., Weir, M.R., Oparil, S., Weber, M., Cady, W.J., Stewart, W.H. JAMA (1990) [Pubmed]
  20. Minocycline treatment of pulmonary nocardiosis. Petersen, E.A., Nash, M.L., Mammana, R.B., Copeland, J.G. JAMA (1983) [Pubmed]
  21. Prazosin and clonidine for moderately severe hypertension. Kirkendall, W.M., Hammond, J.J., Thomas, J.C., Overturf, M.L., Zama, A. JAMA (1978) [Pubmed]
  22. Thioridazine-induced torsade de pointes. Successful therapy with isoproterenol. Kemper, A.J., Dunlap, R., Pietro, D.A. JAMA (1983) [Pubmed]
  23. Nortriptyline in depressed patients with left ventricular impairment. Roose, S.P., Glassman, A.H., Giardina, E.G., Johnson, L.L., Walsh, B.T., Woodring, S., Bigger, J.T. JAMA (1986) [Pubmed]
  24. Oropharyngeal decontamination decreases incidence of ventilator-associated pneumonia. A randomized, placebo-controlled, double-blind clinical trial. Pugin, J., Auckenthaler, R., Lew, D.P., Suter, P.M. JAMA (1991) [Pubmed]
  25. Acupuncture and amitriptyline for pain due to HIV-related peripheral neuropathy: a randomized controlled trial. Terry Beirn Community Programs for Clinical Research on AIDS. Shlay, J.C., Chaloner, K., Max, M.B., Flaws, B., Reichelderfer, P., Wentworth, D., Hillman, S., Brizz, B., Cohn, D.L. JAMA (1998) [Pubmed]
  26. Is cocaine a sympathetic stimulant during general anesthesia? Barash, P.G., Kopriva, C.J., Langou, R., VanDyke, C., Jatlow, P., Stahl, A., Byck, R. JAMA (1980) [Pubmed]
  27. Depression masquerading as diabetic neuropathy. Turkington, R.W. JAMA (1980) [Pubmed]
  28. Regulation of tumor invasion by cartilage-derived anti-invasion factor in vitro. Pauli, B.U., Memoli, V.A., Kuettner, K.E. J. Natl. Cancer Inst. (1981) [Pubmed]
  29. Effect of lucanthone hydrochloride on the radiation response of intestine and bone marrow of the Chinese hamster. Milligan, A.J., Katz, H.R., Leeper, D.B. J. Natl. Cancer Inst. (1978) [Pubmed]
  30. Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit. Holdsworth, S.R., Tipping, P.G. J. Clin. Invest. (1985) [Pubmed]
  31. The effects of psychosocial services in substance abuse treatment. McLellan, A.T., Arndt, I.O., Metzger, D.S., Woody, G.E., O'Brien, C.P. JAMA (1993) [Pubmed]
  32. Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting. EPISTENT Investigators. Evaluation of Platelet IIb/IIIa Inhibitor for Stenting. Steinhubl, S.R., Tan, W.A., Foody, J.M., Topol, E.J. JAMA (1999) [Pubmed]
  33. Successful treatment of naturally occurring influenza A/USSR/77 H1N1. Van Voris, L.P., Betts, R.F., Hayden, F.G., Christmas, W.A., Douglas, R.G. JAMA (1981) [Pubmed]
  34. Cholinesterase inhibition for Alzheimer disease: a meta-analysis of the tacrine trials. Dementia Trialists' Collaboration. Qizilbash, N., Whitehead, A., Higgins, J., Wilcock, G., Schneider, L., Farlow, M. JAMA (1998) [Pubmed]
  35. Heroin detoxification. A comparison of propoxyphene and methadone. Tennant, F.S., Russell, B.A., Casas, S.K., Bleich, R.N. JAMA (1975) [Pubmed]
  36. The mechanisms of [URE3] prion elimination demonstrate that large aggregates of Ure2p are dead-end products. Ripaud, L., Maillet, L., Cullin, C. EMBO J. (2003) [Pubmed]
  37. Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage. Shimizu, T., O'Connor, P.M., Kohn, K.W., Pommier, Y. Cancer Res. (1995) [Pubmed]
  38. Induction of aromatase (CYP19) expression in breast cancer cells through a nongenomic action of estrogen receptor alpha. Kinoshita, Y., Chen, S. Cancer Res. (2003) [Pubmed]
  39. Protein kinase C regulates Fas (CD95/APO-1) expression. Wang, R., Zhang, L., Yin, D., Mufson, R.A., Shi, Y. J. Immunol. (1998) [Pubmed]
  40. Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. Liang, M., Mallari, C., Rosser, M., Ng, H.P., May, K., Monahan, S., Bauman, J.G., Islam, I., Ghannam, A., Buckman, B., Shaw, K., Wei, G.P., Xu, W., Zhao, Z., Ho, E., Shen, J., Oanh, H., Subramanyam, B., Vergona, R., Taub, D., Dunning, L., Harvey, S., Snider, R.M., Hesselgesser, J., Morrissey, M.M., Perez, H.D. J. Biol. Chem. (2000) [Pubmed]
  41. The pharmacokinetics of heroin in patients with chronic pain. Inturrisi, C.E., Max, M.B., Foley, K.M., Schultz, M., Shin, S.U., Houde, R.W. N. Engl. J. Med. (1984) [Pubmed]
  42. Activation of apical chloride channels in the gastric oxyntic cell. Demarest, J.R., Loo, D.D., Sachs, G. Science (1989) [Pubmed]
  43. Are esophageal motility abnormalities produced during the intraesophageal acid perfusion test? Richter, J.E., Johns, D.N., Wu, W.C., Castell, D.O. JAMA (1985) [Pubmed]
  44. Aptiganel hydrochloride in acute ischemic stroke: a randomized controlled trial. Albers, G.W., Goldstein, L.B., Hall, D., Lesko, L.M. JAMA (2001) [Pubmed]
  45. Treatment of anorectal gonorrhea infections in men. Sands, M. JAMA (1980) [Pubmed]
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