Disease relevance of Scillaren

• Cholestasis induced by scillaren administration, bicarbonate deprivation, or reduced hepatic blood flow [1].

High impact information on Scillaren

• Fresh bulbs of Urginea sanguinea yielded stigmasterol, phloroglucinol, phloroglucinol 1-beta-D-glucopyranoside (phlorin), scillaren A, a novel compound 5 alpha-4,5-dihydroscillaren A (1), salicylic acid, and 3-hydroxy-4-methylbenzoic acid [2].
• Finally, we show that variations in the monovalent cation content of the buffer, or the addition of an ion transport inhibitor (scillaren), or an ionophore (valinomycin) all affect the ratio of stalk cells to spores [3].
• There was a large (approx. 3 mmol/l red blood cells per h) scillaren-sensitive, Na-Na exchange diffusion component present under K-free conditions [4].

References