Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

roxithromycin (3R,4S,5S,6R,7R,9R,10E,11S,12R ,13R,14R)-6...

Synonyms:

González de la Huebra, M.J. et al., Fernandes, P.B. et al., Inui, S. et al.

González de la Huebra, Bordin, Rodríguez, Inui, Nakao, Itami,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of roxithromycin

5. All the macrolides were bacteriostatic against Staphylococcus aureus 553, except RO and MI which were slowly bactericidal [1].

High impact information on roxithromycin

RESULTS: The result showed that 5 microg/ml of RXM suppress 10(-9)M R1881-induced AR transcriptional activity by 21.2% [2].
A high-performance liquid chromatography (HPLC) method using chromatographic conditions optimised in a previous work was applied for the separation of three macrolide antibiotics roxithromycin (Rox), oleandomycin (Ole) and rosamicin (Ros) and further determination of two of them, roxithromycin (Rox) and oleandomycin (Ole), in human urine samples [3].

References

Comparative in vitro potencies of nine new macrolides. Fernandes, P.B., Hardy, D.J. Drugs under experimental and clinical research. (1988) [Pubmed]
Modulation of androgen receptor transcriptional activity by anti-acne reagents. Inui, S., Nakao, T., Itami, S. J. Dermatol. Sci. (2004) [Pubmed]
Comparative study of coulometric and amperometric detection for the determination of macrolides in human urine using high-performance liquid chromatography. González de la Huebra, M.J., Bordin, G., Rodríguez, A.R. Analytical and bioanalytical chemistry. (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share