Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Sumarotene 1,1,4,4-tetramethyl-6-[(E)-1- (4...

Synonyms: Sumaroteno, Sumarotenum, SureCN449752, CHEMBL2105526, AC1O5L5G, ...

Misiewicz, J. et al., Edelmann, A. et al.

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Disease relevance of Arotinoid methyl sulphone

The mean percent decrease in the number of actinic keratoses was 37.8% for areas treated with Ro 14-9706 and 30.3% for areas treated with tretinoin [1].

High impact information on Arotinoid methyl sulphone

Thus, the arotinoid Ro 14-9706 exhibits in rats a prolactin-suppressive activity which affects lactation and subsequently pup survival [2].

References

Topical treatment of multiple actinic keratoses of the face with arotinoid methyl sulfone (Ro 14-9706) cream versus tretinoin cream: a double-blind, comparative study. Misiewicz, J., Sendagorta, E., Golebiowska, A., Lorenc, B., Czarnetzki, B.M., Jablonska, S. J. Am. Acad. Dermatol. (1991) [Pubmed]
Prolactin lowering activity of the retinoid Ro 14-9706 affecting lactation and pup survival. Edelmann, A., Galli, B., Hennes, U., Kistler, A., Kuhn, H., Mettler, F. Arch. Toxicol. (1994) [Pubmed]

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