The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

Table of contents

About

Terms

 

Chemical Compound Review: 

Quene 1     2-[[2-[(E)-2-[2- (bis(carboxymethyl)amino)p...

Synonyms: SureCN8653495, AC1O5QTE
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Quene 1

  • Intracellular pH can be measured at intracellular quene 1 concentrations of approximately 0.1 mM and quene 1 does not perturb glycolysis or the ATP level in resting cells at concentrations up to 0.8 mM [1].
  • Photometric fluorescence microscopy has been used to measure intracellular pH (pHi) and free calcium concentrations [( Ca]i) in individual mouse thymocytes and 2H3 rat basophil leukaemic cells containing indicators for pH (quene 1) or calcium (quin 2) [2].
  • The pH in synaptosomes estimated by the indicator quene 1 is 7.04 +/- 0.07 and is stable in media containing 5 mM bicarbonate [3].

References

  1. Intracellular pH of stimulated thymocytes measured with a new fluorescent indicator. Rogers, J., Hesketh, T.R., Smith, G.A., Metcalfe, J.C. J. Biol. Chem. (1983) [Pubmed]
  2. Intracellular pH and free calcium changes in single cells using quene 1 and quin 2 probes and fluorescence microscopy. Rogers, J., Hesketh, T.R., Smith, G.A., Beaven, M.A., Metcalfe, J.C., Johnson, P., Garland, P.B. FEBS Lett. (1983) [Pubmed]
  3. Changes in free-calcium levels and pH in synaptosomes during transmitter release. Richards, C.D., Metcalfe, J.C., Smith, G.A., Hesketh, T.R. Biochim. Biophys. Acta (1984) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities