Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1O52OD [(2R,4S,5S)-3- (acetyloxymethyl)-2- [(2R,3R...

Synonyms:

Qian-Cutrone, J. et al.

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Disease relevance of Niruriside

Niruriside, a new HIV REV/RRE binding inhibitor from Phyllanthus niruri [1].

High impact information on Niruriside

Niruriside showed specific inhibitory activity against the binding of REV protein to RRE RNA with an IC50 value of 3.3 microM; however, niruriside did not protect CEM-SS cells from acute HIV infection at concentrations up to 260 microM using an XTT dye reduction assay [1].

References

Niruriside, a new HIV REV/RRE binding inhibitor from Phyllanthus niruri. Qian-Cutrone, J., Huang, S., Trimble, J., Li, H., Lin, P.F., Alam, M., Klohr, S.E., Kadow, K.F. J. Nat. Prod. (1996) [Pubmed]

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