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Chemical Compound Review:

Bianthrone 10-(10-oxoanthracen-9- ylidene)anthracen-9-one

Synonyms: bisanthrone, SureCN769933, ANW-63130, NSC-89778, NSC-627656, ...

Mbwambo, Z.H. et al.

Mbwambo, Apers, Moshi, Kapingu, Van Miert, Claeys, Brun, Cos, Pieters, Vlietinck,

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High impact information on Dehydrodianthrone

A phytochemical investigation of the 80% ethanolic extract of stem bark of Vismia orientalis Engl. (Guttiferae or Clusiaceae), a plant used in traditional medicine in Tanzania, resulted in the isolation and spectroscopic characterisation of 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone, emodin, vismione D and bianthrone A1 [1].

Associations of Dehydrodianthrone with other chemical compounds

Other antiprotozoal activities observed for emodin against both Trypanosoma species and P. falciparum, for bianthrone A1 against T. b. rhodesiense and P. falciparum, and for 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone against T. b. rhodesiense, L. donovani and P. falciparum were in the range of 10 to 50 micrograms/mL [1].

References

Anthranoid compounds with antiprotozoal activity from Vismia orientalis. Mbwambo, Z.H., Apers, S., Moshi, M.J., Kapingu, M.C., Van Miert, S., Claeys, M., Brun, R., Cos, P., Pieters, L., Vlietinck, A. Planta Med. (2004) [Pubmed]

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