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Chemical Compound Review:

PubChem3378 1-(2,6- dihydroxyphenyl)ethanone

Synonyms: NSC-615, NSC615, CHEMBL454739, SureCN105807, AG-B-77564, ...

Zehl, M. et al., Rezk, B.M. et al., Smith, T.A. et al.

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High impact information on gamma-Resacetophenone

Comparison with structurally related compounds revealed that the antioxidant pharmacophore of phloretin is 2,6-dihydroxyacetophenone [1].
Inhalation of dried 2,6-dihydroxyacetophenone produces nasal irritation and sneezing at short-term exposures of around 1 mg m-3 [2].

Analytical, diagnostic and therapeutic context of gamma-Resacetophenone

The MALDI matrix 2,6-dihydroxyacetophenone facilitated the formation of highly abundant [M + 2H](2+) ions with good resolution compared to other matrices in a linear TOF instrument [3].

References

The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids. Rezk, B.M., Haenen, G.R., van der Vijgh, W.J., Bast, A. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
Study of the acute human health effects of intermediates in the synthesis of sodium cromoglycate. Smith, T.A., Mashingaidze, M. The Annals of occupational hygiene. (1995) [Pubmed]
Characterization of covalently inhibited extracellular lipase from Streptomyces rimosus by matrix-assisted laser desorption/ionization time-of-flight and matrix-assisted laser desorption/ionization quadrupole ion trap reflectron time-of-flight mass spectrometry: localization of the active site serine. Zehl, M., Lescić, I., Abramić, M., Rizzi, A., Kojić-Prodić, B., Allmaier, G. Journal of mass spectrometry : JMS. (2004) [Pubmed]

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