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Chemical Compound Review:

Gentisamide 2,5-dihydroxybenzamide

Synonyms: AG-F-78566, SureCN1163541, CTK4J5864, AR-1D4339, KB-225928, ...

Xu, X. et al., Xu, X. et al.

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High impact information on AIDS018405

SAM and its six metabolites, salicylamide sulphate, salicylamide glucuronide, gentisamide (GAM), gentisamide 2-sulphate, gentisamide 5-sulphate and gentisamide 5-glucuronide, were separated on a mu Bondapak C18 column with 0.085 M potassium dihydrogenphosphate pH 3.35, as mobile phase and by using a flow gradient [1].
Hepatic modeling of metabolite kinetics in sequential and parallel pathways: salicylamide and gentisamide metabolism in perfused rat liver [2].

References

High-performance liquid chromatographic method for the quantitation of salicylamide and its metabolites in biological fluids. Xu, X., Pang, K.S. J. Chromatogr. (1987) [Pubmed]
Hepatic modeling of metabolite kinetics in sequential and parallel pathways: salicylamide and gentisamide metabolism in perfused rat liver. Xu, X., Pang, K.S. Journal of pharmacokinetics and biopharmaceutics. (1989) [Pubmed]

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