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Chemical Compound Review

Amidosal     2-hydroxybenzamide

Synonyms: Dolomide, Panithal, Salamide, Saliamid, Saliamin, ...
 
 
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Disease relevance of Cetamide

 

High impact information on Cetamide

 

Chemical compound and disease context of Cetamide

 

Biological context of Cetamide

 

Anatomical context of Cetamide

 

Associations of Cetamide with other chemical compounds

 

Gene context of Cetamide

  • A photoaffinity probe, 2-(4-phosphopentamanniminophenyl)ethyl-(4-azido) salicylamide, was prepared for photolabelling of the mannose 6-phosphate/insulin-like growth factor II receptor [26].
  • By analysis of the metabolic profile of RB, and by inhibition of glucuronidation (the main metabolic route) with salicylamide, we show in this paper that formation and secretion of RB-conjugates from liver into perfusate is not involved in the reappearance and redistribution phenomena [27].
  • The total solubility of salicylamide increased nonlinearly at lower antihistamine concentrations (less than 0.4 M), but reached limiting linearity (slope = 0.34 mol/mol of antihistamine) at higher concentrations (up to 0.8 M) [28].
  • Following diethyl ether extraction, 4NC and the assay internal standard (salicylamide) were separated by reversed-phase (C18) liquid chromatography [29].
  • Sulfatase and beta-glucuronidase treatment allowed the analysis of plasma sulfate and glucuronide conjugates as free salicylamide [30].
 

Analytical, diagnostic and therapeutic context of Cetamide

References

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  15. Effect of salicylamide on the placental transfer and fetal tissue distribution of sodium-35S-sulfate in the rat. Knight, E., Van Wart, J., Roe, D.A. J. Nutr. (1978) [Pubmed]
  16. Effect of route of administration on competitive drug biotransformation interaction: salicylamide-ascorbic acid interaction in rats. Houston, J.B., Levy, G. J. Pharmacol. Exp. Ther. (1976) [Pubmed]
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  19. Extrahepatic extraction of salicylamide in dogs. Fielding, R.M., Waschek, J.A., Effeney, D.J., Pogany, A.C., Pond, S.M., Tozer, T.N. J. Pharmacol. Exp. Ther. (1986) [Pubmed]
  20. Effect of product inhibition on elimination kinetics of ethoxybenzamide in rabbits. Analysis by physiological pharmacokinetic model. Lin, J.H., Sugiyama, Y., Hanano, M., Awazu, S. Drug Metab. Dispos. (1984) [Pubmed]
  21. Vectorial release of sulfoconjugates in the vascularly perfused mouse small intestine. Wollenberg, P., Rummel, W. Biochem. Pharmacol. (1984) [Pubmed]
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  23. Inhibition by salicylamide of 7,12-dimethylbenz[a]anthracene-evoked DNA excision repair in isolated rat hepatocytes: an indication of the involvement of a sulfate ester intermediate in carcinogenesis? Brouns, R.M., Van Doorn, R., Bos, R.P., Henderson, P.T. Mutat. Res. (1980) [Pubmed]
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  25. 3-Hydroxylation of salicylamide in mice. Howell, S.R., Kotkoskie, L.A., Dills, R.L., Klaassen, C.D. Journal of pharmaceutical sciences. (1988) [Pubmed]
  26. Preparation of a photoaffinity probe for the Man6P/IGF-II receptor. Miyagishima, T., Gasa, S., Honke, K., Miyazaki, T., Makita, A. Biol. Chem. Hoppe-Seyler (1993) [Pubmed]
  27. Zonal compartmentation of perfused rat liver: plasma reappearance of rhodamine B explained. Braakman, I., Groothuis, G.M., Meijer, D.K. J. Pharmacol. Exp. Ther. (1989) [Pubmed]
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  29. High-performance liquid chromatographic assay for 4-nitrophenol hydroxylation, a putative cytochrome P-4502E1 activity, in human liver microsomes. Tassaneeyakul, W., Veronese, M.E., Birkett, D.J., Miners, J.O. J. Chromatogr. (1993) [Pubmed]
  30. Radiochemical plasma salicylamide assay using ring-labeled tritiated salicylamide. Stella, V.J., Varia, S.A., Riedy, M. Journal of pharmaceutical sciences. (1979) [Pubmed]
  31. Sodium salicylamide: relative bioavailability and subjective effects. Fleckenstein, L., Mundy, G.R., Horovitz, R.A., Mazzullo, J.M. Clin. Pharmacol. Ther. (1976) [Pubmed]
  32. Effects of aspirin-like drugs on mitogen-stimulated DNA synthesis of lymphocytes from pregnant rats and offspring. Millis, R.M., Ewii, M.C., Offiah, G.U., Hyde, B.P., Knight, E.M. Pediatr. Res. (1988) [Pubmed]
 
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