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Chemical Compound Review:

AR-1D9911 (2S,3S,4S,5R,6S)-6-(2- aminocarbonylphenoxy...

Synonyms: AR-1D9912, AC1L4P2G, AC1Q5G9T, Salicylamide glucuronide

Adachi, Y. et al., Meloni, T. et al., Cutillo, S. et al.

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Disease relevance of Salicylamide glucuronide

Salicylamide-Glucuronide formation in children with favism and in their parents [1].
The percent of SAMG in cases with unconjugated hyperbilirubinemias of other geneses were almost within normal limits [2].
The percent of SAMG of 0-6 hours-urine specimens was 57.2 +/- 8.6 in acute hepatitis, 66.6 +/- 10.9 in chronic hepatitis, and 48.6 +/- 10.7 in liver cirrhosis (mean +/- S.D.). Free salicylamide increased slightly in liver diseases [2].

High impact information on Salicylamide glucuronide

Salicylamide glucuronide formation in newborn babies with G-6-PD deficiency [3].
After rifampicin or phenytoin administration, the percent of SAMG of the patients with lung tuberculosis or epilepsy did not surpass that of NV [2].

Anatomical context of Salicylamide glucuronide

Salicylamide glucuronide formation has been studied in 23 newborn babies with erythrocyte G-6-PD deficiency and in 15 normal newborns on the first day of life [3].

References

Salicylamide-Glucuronide formation in children with favism and in their parents. Cutillo, S., Costa, S., Vintuleddu, M.C., Meloni, T. Acta Haematol. (1976) [Pubmed]
Salycylamide glucuronide formation in liver disease and its change by drugs. Adachi, Y., Wakisaka, G., Yamamoto, T. Gastroenterol. Jpn. (1975) [Pubmed]
Salicylamide glucuronide formation in newborn babies with G-6-PD deficiency. Meloni, T., Costa, S., Corti, R., Cutillo, S. Biol. Neonate (1978) [Pubmed]

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