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Chemical Compound Review:

Tessalin 2-[2-[2-[2-[2-[2-[2-[2-(2...

Synonyms: Tessalon, Zonatuss, Exangit, Tesalon, Ventussin, ...

Mongan, P.D. et al., Crouch, B.I. et al., Cohan, J.A. et al.

Crouch, Knick, Crouch, Matsumura, Rollins,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Tessalon Perles

Benzonatate overdose associated with seizures and arrhythmias [1].
We report 2 cases of benzonatate poisoning with seizures and cardiac arrest and an analytical method to identify and quantify benzonatate in human plasma [1].

High impact information on Tessalon Perles

MEASUREMENTS AND MAIN RESULTS: The time to obtain oropharyngeal anesthesia was measured as the time from obtaining the benzonatate capsules from the bottle or palpation of the neck to locate the hyoid bone to the time when the patient exhibited an absent gag response to an oropharyngeal airway [2].

Analytical, diagnostic and therapeutic context of Tessalon Perles

Quantitative analysis of benzonatate is possible using high-pressure liquid chromatography with tandem mass spectrometry [1].
STUDY OBJECTIVE: To determine whether sodium benzonatate (Tessalon Perles) can provide rapid, effective topical oral anesthesia in preparation for awake intubations [2].
Two fatal cases involving Tessalon (benzonatate) were quantitated by ultraviolet (UV) and high performance liquid chromatography (HPLC) [3].

References

Benzonatate overdose associated with seizures and arrhythmias. Crouch, B.I., Knick, K.A., Crouch, D.J., Matsumura, K.S., Rollins, D.E. J. Toxicol. Clin. Toxicol. (1998) [Pubmed]
Rapid oral anesthesia for awake intubation. Mongan, P.D., Culling, R.D. Journal of clinical anesthesia. (1992) [Pubmed]
Two fatalities resulting from Tessalon (benzonatate). Cohan, J.A., Manning, T.J., Lukash, L., Long, C., Ziminski, K.R., Conradi, S.E. Veterinary and human toxicology. (1986) [Pubmed]

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