Disease relevance of Intubation

• Rats at 7 weeks of age received intragastric intubations of PhIP (85 mg / kg body weight) 4 times weekly for 2 weeks and were maintained on control diet (high fat diet) or experimental diet (high fat diet supplemented with 400 ppm nimesulide) throughout the experiment [1].
• RESULTS: Both ages showed similar ethanol-induced tachycardia and activity suppression; however, adolescents were found to be more sensitive than adults to the hypothermic effect of ethanol, data opposite other results from our laboratory and elsewhere using intragastric intubations or intraperitoneal administrations of ethanol [2].
• The patient group intubated with SUX was characterized by a greater percentage of women (48% vs 35%; P less than .05), a higher mean Glasgow Coma Scale score (8.6 vs 3.4), fewer intubations for cardiac arrest (3% vs 81%), and more hospital survivors (58% vs 24%; P less than .005) [3].
• CONCLUSIONS: Early bubble CPAP reduced delivery room intubations, days on mechanical ventilation, postnatal steroid use and was associated with increased postnatal weight gain with no increased complications [4].

High impact information on Intubation

• Groups of Charles River Sprague-Dawley male rats were given intragastric intubations of methylbenzylnitrosamine after receiving one of the following diets for 4 weeks: control, zinc-deficient, or zinc-deficient diet plus 4% ethanol in the drinking water [5].
• Although the rate of ETI was lower among COPD patients receiving NPPV, this trend did not reach statistical significance (5.26 intubations versus 15.63 intubations per 100 ICU days, p = 0.12, NPPV versus UMC, respectively) [6].
• Initial time course intubations using adrenals from a single donor generally demonstrated that minces and suspensions had a greater steroid production compared with slices [7].
• Feeding of retinyl acetate (0.2 mM) or N-(4-hydroxyphenyl) retinamide (4-HPR) (1.0 mM) for 27 weeks to female BD2F1 mice previously treated with a series of gastric intubations of 7,12-dimethylbenzanthracene (DMBA), did not significantly affect the incidence of mammary tumors [8].
• The number of tracheal intubations that the trainees were required to perform before acquiring expertise in LEI was estimated [9].

Chemical compound and disease context of Intubation

• The fungicide thiram (tetramethylthiuram disulfide, TMTD) was administered by repeated oral intubations to groups of male B6C3F1 mice at 100, 300 and 900 mg/kg body weight for 4 consecutive days, or at 300 mg/kg for 8 and 12 days [10].

Biological context of Intubation

• METHODS: Two hundred patients having thoracic surgery requiring DLT insertion were prospectively studied. "Blind" tracheal intubations were done with 163 left-sided and 37 right-sided disposable polyvinyl chloride Robertshaw tubes [11].
• All intubations were performed after induction of anesthesia with fentanyl and propofol and muscle relaxation with vecuronium [12].

Anatomical context of Intubation

• Periodic intubations of rats with solutions of fluoride (F) lead to the appearance of bands of disrupted pigmentation in continuously erupting incisors [13].
• In two patients in the propofol group the tracheas were moderately difficult to intubate but there were no failed intubations in either group [14].
• Rats trained to alternately shuttle between nose poke and lever operanda for rewarding stimulation to the medial forebrain bundle, were tested following intragastric intubations of ethanol (18%, 1.35 g/kg), Ro 15-4513 (3 mg/kg in 18% ethanol), or vehicle [15].
• To further examine the regulation of TRL on ob mRNA expression, differentiated 3T3-L1 adipocytes were treated with TRL collected from rats fed 5 ml soybean oil by gastric intubations [16].

Associations of Intubation with chemical compounds

• BACKGROUND: The optimal site for monitoring neuromuscular blockade for intubations facilitated with mivacurium chloride has not been established [17].
• It is concluded that intubations of high concentrations of lactose into fasted weanling rats can cause an increase in the absorption and uptake of lead [18].
• Group Unintubated Control (from separate litters) did not receive any intubations [19].
• Control rats either received the same periodic F intubations or were maintained on the low-F diet without intubation [13].
• In half of the animals the withdrawal reaction was attenuated during the first nine weekly episodes by intragastric intubations with phenobarbital [20].

Gene context of Intubation

• To see whether the effects of ciprofibrate could be imitated, rats were given another PPAR alpha ligand WY-14643 or the PPAR gamma ligand troglitazone by gastric intubations daily for 28 and 56 days [21].
• Distribution of intubations by level of EM training was PGY1, 5%; PGY2, 52%; PGY3, 40%; and attendings, 3% [22].
• As judged by the author(s) on the morning after the intubation, correct initial placement was achieved in 69 (78%) of 88 intubations using the new system, compared with 71 (66%) of 107 using the standard technique (Fisher's Test, one-tailed, P = .044) [23].
• The LTA cannula and difficult intubations [24].
• This hypothesis was supported by the different distributions of Cd in the liver and kidney after Cd-MT and CdCl2 intubations [25].

Analytical, diagnostic and therapeutic context of Intubation

• Half the rats in each group received intragastric intubation with nimodipine daily for 14 days after transplantation surgery, whereas the other half received control intubations [26].
• Hepatic bile flow and its bile acid composition were determined in a group of 23 rats receiving 20% (W/v) ethanol by daily intubations 5 times a week over a 10-12 week period and in a control group of 23 rats [27].

References