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Chemical Compound Review

P7703_ALDRICH     pentane-1,5-diol

Synonyms: CHEMBL448289, NSC-5927, AG-D-29556, ACMC-209997, ANW-16265, ...
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Disease relevance of Pentylene glycol


High impact information on Pentylene glycol


Biological context of Pentylene glycol

  • When used in pharmaceutical topical preparations, pentane-1,5-diol will increase the percutaneous absorption of the active substance and it is an efficient antimicrobial agent that will act as an effective preservative in topical formulations [3].

Associations of Pentylene glycol with other chemical compounds


  1. The in vitro activity of pentane-1,5-diol against aerobic bacteria. A new antimicrobial agent for topical usage? Faergemann, J., Hedner, T., Larsson, P. Acta Derm. Venereol. (2005) [Pubmed]
  2. Treatment of atopic dermatitis with 1% hydrocortisone and 25% pentane-1,5-diol: effect on Staphylococcus aureus. Sandström Falk, M.H., Särnhult, T., Hedner, T., Faergemann, J. Acta Derm. Venereol. (2006) [Pubmed]
  3. Pentane-1,5-diol as a percutaneous absorption enhancer. Faergemann, J., Wahlstrand, B., Hedner, T., Johnsson, J., Neubert, R.H., Nyström, L., Maibach, H. Arch. Dermatol. Res. (2005) [Pubmed]
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