Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

PubChem15052 4-amino-5-chloro-2-methoxy- benzoic acid

Synonyms: SureCN99019, AG-C-90921, AG-E-56670, AG-G-83211, ACMC-209oll, ...

Maurich, V. et al., Yang, D. et al.

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High impact information on ZINC00036685

New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors [1].
The synthesis of 2-(4-amino-5-chloro-2-methoxybenzamido)acetic acid 2, a metabolite of metoclopramide 1, has been accomplished through the coupling of 4-amino-5-chloro-2-methoxybenzoic acid 4 with glycine benzyl ester followed by a catalytic hydrogenation [2].

References

New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. Yang, D., Soulier, J.L., Sicsic, S., Mathé-Allainmat, M., Brémont, B., Croci, T., Cardamone, R., Aureggi, G., Langlois, M. J. Med. Chem. (1997) [Pubmed]
Synthesis of a metabolite of metoclopramide and its detection in human urine. Maurich, V., De Amici, M., De Micheli, C. Farmaco (1994) [Pubmed]

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