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Chemical Compound Review

Palatone     3-hydroxy-2-methyl-pyran-4-one

Synonyms: MALTOL, Talmon, Veltol, Vetol, Larixinic acid, ...
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Disease relevance of MALTOL


High impact information on MALTOL


Gene context of MALTOL

  • Prolonged treatments with APT, MAL and Vit E significantly reduced the mortality in animals receiving multiple dose of DOX (3 mg/kg x 4) [1].


  1. A new antithrombotic agent, aspalatone, attenuated cardiotoxicity induced by doxorubicin in the mouse; possible involvement of antioxidant mechanism. Kim, C., Nam, S.W., Choi, D.Y., Choi, J.H., Park, E.S., Jhoo, W.K., Kim, H.C. Life Sci. (1997) [Pubmed]
  2. Maltol (3-hydroxy-2-methyl-4-pyrone) toxicity in neuroblastoma cell lines and primary murine fetal hippocampal neuronal cultures. Hironishi, M., Kordek, R., Yanagihara, R., Garruto, R.M. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. (1996) [Pubmed]
  3. The absence of extracellular calcium potentiates the killing of cultured hepatocytes by aluminum maltolate. Snyder, J.W., Serroni, A., Savory, J., Farber, J.L. Arch. Biochem. Biophys. (1995) [Pubmed]
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