Chemical Compound Review:
CHEMBL304572 3-(3-oxo-1H-isoindol-2- yl)piperidine-2,6...
Synonyms:
SureCN476917, AG-E-83843, ACMC-20mb5l, EM 12, AC1L3MDG, ...
- The thalidomide analog, EM 12, enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas. Gershbein, L.L. Cancer Lett. (1991)
- Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. Muller, G.W., Chen, R., Huang, S.Y., Corral, L.G., Wong, L.M., Patterson, R.T., Chen, Y., Kaplan, G., Stirling, D.I. Bioorg. Med. Chem. Lett. (1999)
- Embryotoxic effects of thalidomide-derivatives in the non-human primate Callithrix jacchus. I. Effects of 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-dioxopiperidine (EM12) on skeletal development. Merker, H.J., Heger, W., Sames, K., Stürje, H., Neubert, D. Arch. Toxicol. (1988)
- The enantiomers of the teratogenic thalidomide analogue EM 12: 1. Chiral inversion and plasma pharmacokinetics in the marmoset monkey. Schmahl, H.J., Nau, H., Neubert, D. Arch. Toxicol. (1988)