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Chemical Compound Review

SureCN198638     2-amino-3-(2H-1,2,4-triazol- 3-yl)propanoic...

Synonyms: NSC-76227, AC1L3NPA, NSC76227, AR-1E6958, LS-192867, ...
 
 
 
 
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Disease relevance of NSC 76227

  • In Serratia marcescens, the mutation responsible for triazolealanine (TRA) resistance was transferred from a TRA-resistant mutant to a urocanase-less mutant by PS20-mediated transduction [1].
 

High impact information on NSC 76227

  • The two crosses were performed using as donors two TRA-resistant mutants, whose phenotypes included increased levels of histidine-biosynthetic enzymes and feedback-insensitive phosphoribosyltransferase [1].

References

  1. Construction of a urocanic acid-producing strain of Serratia marcescens by transduction. Kisumi, M., Nakanishi, N., Takagi, T., Chibata, I. Appl. Environ. Microbiol. (1978) [Pubmed]
 
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