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Gene Review

TRAIP  -  TRAF interacting protein

Homo sapiens

Synonyms: E3 ubiquitin-protein ligase TRAIP, RING finger protein 206, RNF206, TRAF-interacting protein, TRIP
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High impact information on TRAIP

  • To shed more light on the function of CYLD, we have performed a yeast two hybrid screen using an HaCaT cDNA library that identified the RING finger protein TRIP (TRAF-interacting protein) as interactor with full-length CYLD [1].
  • The lithium complexes Ar(C6H4-2-CH2NMe2)PLi undergo metathesis reactions with either NaOBut or KOBut to give the heavier alkali metal phosphides {Ar(C6H4-2-CH2NMe2)P}M.1/2OEt2 [Ar = mes, M = Na (8), K (9); Ar = Tripp, M = K (10)] [2].


  1. The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor. Regamey, A., Hohl, D., Liu, J.W., Roger, T., Kogerman, P., Toftgard, R., Huber, M. J. Exp. Med. (2003) [Pubmed]
  2. Amino-functionalised diarylphosphide complexes of the alkali metals and lanthanum. Izod, K., Liddle, S.T., Clegg, W., Harrington, R.W. Dalton transactions (Cambridge, England : 2003) (2006) [Pubmed]
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