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Gene Review:

uvrC - excinuclease ABC subunit C

Escherichia coli CFT073

Crowley, D.J. et al., Kondoh, H.

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Disease relevance of uvrC

In Escherichia coli K-12, 11 fla genes and a hag gene are located between his and uvrC, making two clusters at map positions 42.5 and 43.0 min [1].

High impact information on uvrC

CONCLUSION: Our results demonstrate that homologs of the bacterial nucleotide excision repair genes uvrA, uvrB, and uvrC are required for the removal of UV damage in the absence of photoreactivating light in Halobacterium sp. NRC-1 [2].

References

Isolation and characterization of nondefective transducing lambda bacteriophages carrying fla genes of Escherichia coli K-12. Kondoh, H. J. Bacteriol. (1977) [Pubmed]
The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1. Crowley, D.J., Boubriak, I., Berquist, B.R., Clark, M., Richard, E., Sullivan, L., Dassarma, S., McCready, S. Saline Syst. (2006) [Pubmed]

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