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Gene Review:

Fltn - flectin

Mus musculus

This record was replaced with 17886.

Tsuda, T. et al.

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Disease relevance of Fltn

In inv/inv mice, a known mouse model for human situs inversus, in which the directionality of heart looping is inverted, flectin expression pattern is mirror image of that of normal mouse embryos during looping stages [1].

High impact information on Fltn

After looping, flectin becomes restricted to the epicardium and subepicardial extracellular regions [1].

References

Differential expression of flectin in the extracellular matrix and left-right asymmetry in mouse embryonic heart during looping stages. Tsuda, T., Majumder, K., Linask, K.K. Dev. Genet. (1998) [Pubmed]

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