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Gene Review:

Imp1 - imprintor 1

Mus musculus

Carlson, L.L. et al., Forejt, J. et al.

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High impact information on Imp1

Genetic analysis of genomic imprinting: an Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus [1].
Changes in methylation patterns in preimplantation embryos are therefore proposed to be under the control of unidentified regulatory factors rather than DNA MTase itself; these regulatory factors could be members of the group that contains the products of the Ssm-1 and Imp-1 genes, which are involved in the regulation of genomic imprinting [2].

References

Genetic analysis of genomic imprinting: an Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus. Forejt, J., Gregorová, S. Cell (1992) [Pubmed]
Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting. Carlson, L.L., Page, A.W., Bestor, T.H. Genes Dev. (1992) [Pubmed]

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