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Gene Review

MYCNOS  -  MYCN opposite strand

Homo sapiens

Synonyms: CYMN, MYCN-AS1, N-CYM, N-cym protein, N-myc opposite strand, ...
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Disease relevance of MYCNOS


High impact information on MYCNOS

  • We have isolated and characterized complementary DNA clones derived from a transcription unit, N-cym, located on the opposite DNA strand to N-myc, with extensive overlap existing between the 5' ends of the two transcription units [2].

Biological context of MYCNOS


Anatomical context of MYCNOS

  • Although other examples of overlapping, opposite-strand eukaryotic genes exist, N-myc and N-cym are unique in that they appear to be coregulated in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid [2].


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