The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

Rfc4  -  replication factor C (activator 1) 4

Mus musculus

Synonyms: A1, AI894123, AU040575, Activator 1 subunit 4, RFC37, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Rfc4

  • BACKGROUND: Both the A1- and A3-adenosine receptors (ARs) have been implicated in mediating the cardioprotective effects of adenosine [1].
  • In addition, the expression of the mouse A1 cDNA protects human HeLa cells from apoptosis when human A1 and A2 proteins are targeted by RNA interference [2].

References

  1. Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function. Funakoshi, H., Chan, T.O., Good, J.C., Libonati, J.R., Piuhola, J., Chen, X., MacDonnell, S.M., Lee, L.L., Herrmann, D.E., Zhang, J., Martini, J., Palmer, T.M., Sanbe, A., Robbins, J., Houser, S.R., Koch, W.J., Feldman, A.M. Circulation (2006) [Pubmed]
  2. Targeting heterogeneous nuclear ribonucleoparticule A1 and A2 proteins by RNA interference promotes cell death in transformed but not in normal mouse cell lines. Patry, C., Lemieux, B., Wellinger, R.J., Chabot, B. Mol. Cancer Ther. (2004) [Pubmed]
 
WikiGenes - Universities