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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ZBTB6  -  zinc finger and BTB domain containing 6

Homo sapiens

Synonyms: ZID, ZNF482, Zinc finger and BTB domain-containing protein 6, Zinc finger protein 482, Zinc finger protein with interaction domain
 
 
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High impact information on ZBTB6

  • In transfection experiments, the ZID POZ domain inhibits DNA binding in NIH-3T3 cells and appears to localize the protein to discrete regions of the nucleus [1].
  • We describe a novel zinc finger protein, ZID (zinc finger protein with interaction domain) [1].
  • Methylation protection was also seen upstream of the DSE over a sequence corresponding to the binding site of a POZ domain-containing protein, ZID, which interacts with components of histone deacetylase complexes [2].

References

  1. The POZ domain: a conserved protein-protein interaction motif. Bardwell, V.J., Treisman, R. Genes Dev. (1994) [Pubmed]
  2. In vivo footprinting studies suggest a role for chromatin in transcription of the human 7SK gene. Boyd, D.C., Greger, I.H., Murphy, S. Gene (2000) [Pubmed]
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