MeSH Review:
Zinc Fingers
- Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome. Pelletier, J., Bruening, W., Kashtan, C.E., Mauer, S.M., Manivel, J.C., Striegel, J.E., Houghton, D.C., Junien, C., Habib, R., Fouser, L. Cell (1991)
- Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2. Person, R.E., Li, F.Q., Duan, Z., Benson, K.F., Wechsler, J., Papadaki, H.A., Eliopoulos, G., Kaufman, C., Bertolone, S.J., Nakamoto, B., Papayannopoulou, T., Grimes, H.L., Horwitz, M. Nat. Genet. (2003)
- Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein. Rice, W.G., Turpin, J.A., Huang, M., Clanton, D., Buckheit, R.W., Covell, D.G., Wallqvist, A., McDonnell, N.B., DeGuzman, R.N., Summers, M.F., Zalkow, L., Bader, J.P., Haugwitz, R.D., Sausville, E.A. Nat. Med. (1997)
- Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein. Boyer, T.G., Martin, M.E., Lees, E., Ricciardi, R.P., Berk, A.J. Nature (1999)
- Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence. Rauscher, F.J., Morris, J.F., Tournay, O.E., Cook, D.M., Curran, T. Science (1990)
- Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation. Shoichet, S.A., Hoffmann, K., Menzel, C., Trautmann, U., Moser, B., Hoeltzenbein, M., Echenne, B., Partington, M., Van Bokhoven, H., Moraine, C., Fryns, J.P., Chelly, J., Rott, H.D., Ropers, H.H., Kalscheuer, V.M. Am. J. Hum. Genet. (2003)
- The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia. Otani, K., Ujike, H., Tanaka, Y., Morita, Y., Kishimoto, M., Morio, A., Uchida, N., Nomura, A., Kuroda, S. Neurosci. Lett. (2005)
- The role of the Ikaros gene in lymphocyte development and homeostasis. Georgopoulos, K., Winandy, S., Avitahl, N. Annu. Rev. Immunol. (1997)
- Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Koshiba-Takeuchi, K., Takeuchi, J.K., Arruda, E.P., Kathiriya, I.S., Mo, R., Hui, C.C., Srivastava, D., Bruneau, B.G. Nat. Genet. (2006)
- Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. Penengo, L., Mapelli, M., Murachelli, A.G., Confalonieri, S., Magri, L., Musacchio, A., Di Fiore, P.P., Polo, S., Schneider, T.R. Cell (2006)
- ESCRT-I Core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Teo, H., Gill, D.J., Sun, J., Perisic, O., Veprintsev, D.B., Vallis, Y., Emr, S.D., Williams, R.L. Cell (2006)
- HIM-8 binds to the X chromosome pairing center and mediates chromosome-specific meiotic synapsis. Phillips, C.M., Wong, C., Bhalla, N., Carlton, P.M., Weiser, P., Meneely, P.M., Dernburg, A.F. Cell (2005)
- Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8. Sugahara, M., Mikawa, T., Kumasaka, T., Yamamoto, M., Kato, R., Fukuyama, K., Inoue, Y., Kuramitsu, S. EMBO J. (2000)
- PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder. Chen, J., Deangelo, D.J., Kutok, J.L., Williams, I.R., Lee, B.H., Wadleigh, M., Duclos, N., Cohen, S., Adelsperger, J., Okabe, R., Coburn, A., Galinsky, I., Huntly, B., Cohen, P.S., Meyer, T., Fabbro, D., Roesel, J., Banerji, L., Griffin, J.D., Xiao, S., Fletcher, J.A., Stone, R.M., Gilliland, D.G. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells. Hosler, B.A., LaRosa, G.J., Grippo, J.F., Gudas, L.J. Mol. Cell. Biol. (1989)
- An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer. Ellison, V., Gerton, J., Vincent, K.A., Brown, P.O. J. Biol. Chem. (1995)
- Specific binding sites in the alcR and alcA promoters of the ethanol regulon for the CREA repressor mediating carbon catabolite repression in Aspergillus nidulans. Kulmburg, P., Mathieu, M., Dowzer, C., Kelly, J., Felenbok, B. Mol. Microbiol. (1993)
- The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour. Lee, S.B., Kolquist, K.A., Nichols, K., Englert, C., Maheswaran, S., Ladanyi, M., Gerald, W.L., Haber, D.A. Nat. Genet. (1997)
- The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Borrow, J., Stanton, V.P., Andresen, J.M., Becher, R., Behm, F.G., Chaganti, R.S., Civin, C.I., Disteche, C., Dubé, I., Frischauf, A.M., Horsman, D., Mitelman, F., Volinia, S., Watmore, A.E., Housman, D.E. Nat. Genet. (1996)
- OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Hata, A., Seoane, J., Lagna, G., Montalvo, E., Hemmati-Brivanlou, A., Massagué, J. Cell (2000)
- The sex-determining region of the mouse Y chromosome encodes a protein with a highly acidic domain and 13 zinc fingers. Mardon, G., Page, D.C. Cell (1989)
- Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations. Kas, K., Voz, M.L., Röijer, E., Aström, A.K., Meyen, E., Stenman, G., Van de Ven, W.J. Nat. Genet. (1997)
- Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Schneider-Maunoury, S., Topilko, P., Seitandou, T., Levi, G., Cohen-Tannoudji, M., Pournin, S., Babinet, C., Charnay, P. Cell (1993)
- Drosophila CBP is required for dorsal-dependent twist gene expression. Akimaru, H., Hou, D.X., Ishii, S. Nat. Genet. (1997)
- Yeast RAD14 and human xeroderma pigmentosum group A DNA-repair genes encode homologous proteins. Bankmann, M., Prakash, L., Prakash, S. Nature (1992)
- Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Georgopoulos, K., Moore, D.D., Derfler, B. Science (1992)
- The ARF1 GTPase-activating protein: zinc finger motif and Golgi complex localization. Cukierman, E., Huber, I., Rotman, M., Cassel, D. Science (1995)
- Functional dissection and sequence of yeast HAP1 activator. Pfeifer, K., Kim, K.S., Kogan, S., Guarente, L. Cell (1989)
- Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Call, K.M., Glaser, T., Ito, C.Y., Buckler, A.J., Pelletier, J., Haber, D.A., Rose, E.A., Kral, A., Yeger, H., Lewis, W.H. Cell (1990)
- Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Haupt, Y., Alexander, W.S., Barri, G., Klinken, S.P., Adams, J.M. Cell (1991)
- Identification of the cell fate gene stalky in Dictyostelium. Chang, W.T., Newell, P.C., Gross, J.D. Cell (1996)
- Determinants of target gene specificity for steroid/thyroid hormone receptors. Umesono, K., Evans, R.M. Cell (1989)
- GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome. Kang, S., Graham, J.M., Olney, A.H., Biesecker, L.G. Nat. Genet. (1997)
- A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Svensson, E.C., Huggins, G.S., Lin, H., Clendenin, C., Jiang, F., Tufts, R., Dardik, F.B., Leiden, J.M. Nat. Genet. (2000)
- Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein. Kuroiwa, Y., Kaneko-Ishino, T., Kagitani, F., Kohda, T., Li, L.L., Tada, M., Suzuki, R., Yokoyama, M., Shiroishi, T., Wakana, S., Barton, S.C., Ishino, F., Surani, M.A. Nat. Genet. (1996)
- Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis. Takeuchi, A., Mishina, Y., Miyaishi, O., Kojima, E., Hasegawa, T., Isobe, K. Nat. Genet. (2003)
- X-linked situs abnormalities result from mutations in ZIC3. Gebbia, M., Ferrero, G.B., Pilia, G., Bassi, M.T., Aylsworth, A., Penman-Splitt, M., Bird, L.M., Bamforth, J.S., Burn, J., Schlessinger, D., Nelson, D.L., Casey, B. Nat. Genet. (1997)
- A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Sukhatme, V.P., Cao, X.M., Chang, L.C., Tsai-Morris, C.H., Stamenkovich, D., Ferreira, P.C., Cohen, D.R., Edwards, S.A., Shows, T.B., Curran, T. Cell (1988)
- Molecular cloning of matrin F/G: A DNA binding protein of the nuclear matrix that contains putative zinc finger motifs. Hakes, D.J., Berezney, R. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Gastric DNA-binding proteins recognize upstream sequence motifs of parietal cell-specific genes. Tamura, S., Wang, X.H., Maeda, M., Futai, M. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer. Silberstein, G.B., Van Horn, K., Strickland, P., Roberts, C.T., Daniel, C.W. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Alanine scanning site-directed mutagenesis of the zinc fingers of transcription factor ADR1: residues that contact DNA and that transactivate. Thukral, S.K., Morrison, M.L., Young, E.T. Proc. Natl. Acad. Sci. U.S.A. (1991)