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Gene Review

ARPP21  -  cAMP-regulated phosphoprotein, 21kDa

Homo sapiens

Synonyms: ARPP-21, R3HDM3, RCS, TARPP, Thymocyte cAMP-regulated phosphoprotein, ...
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High impact information on ARPP-21

  • Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue [1].
  • In this study we have isolated and sequenced human cDNAs for the phosphoproteins DARPP-32, ARPP-21, and ARPP-16/19, and have compared these sequences to previously characterized bovine and rat cDNAs [1].
  • High levels of ARPP-16/19 and ARPP-21 mRNA were also found in the cerebellar cortex, where they were confined to deeper layers [1].

Other interactions of ARPP-21

  • ARPP-21 and DARPP-32 mRNA, on the other hand, were present in lower levels in neocortical regions [1].

Analytical, diagnostic and therapeutic context of ARPP-21


  1. Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue. Brené, S., Lindefors, N., Ehrlich, M., Taubes, T., Horiuchi, A., Kopp, J., Hall, H., Sedvall, G., Greengard, P., Persson, H. J. Neurosci. (1994) [Pubmed]
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