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Gene Review

TUBGCP2  -  tubulin, gamma complex associated protein 2

Homo sapiens

Synonyms: GCP-2, GCP2, Gamma-ring complex protein 103 kDa, Gamma-tubulin complex component 2, Grip103, ...
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High impact information on TUBGCP2

  • Recently, major advances have been achieved through the finding that gamma-tubulin, Spc97p and Spc98p form a conserved core that is probably responsible for microtubule nucleation, and by the discovery that a yeast GTBP is regulated in a cell-cycle-dependent manner and in response to an external signal [1].

Other interactions of TUBGCP2

  • Surprisingly, h76p shares partial sequence identity with human centrosomal proteins h103p and h104p, suggesting a common protein core [2].


  1. gamma-tubulin complexes: binding to the centrosome, regulation and microtubule nucleation. Schiebel, E. Curr. Opin. Cell Biol. (2000) [Pubmed]
  2. Human 76p: A new member of the gamma-tubulin-associated protein family. Fava, F., Raynaud-Messina, B., Leung-Tack, J., Mazzolini, L., Li, M., Guillemot, J.C., Cachot, D., Tollon, Y., Ferrara, P., Wright, M. J. Cell Biol. (1999) [Pubmed]
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