The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

TUBGCP4  -  tubulin, gamma complex associated protein 4

Homo sapiens

Synonyms: 76P, FLJ14797, GCP-4, GCP4, Gamma-ring complex protein 76 kDa, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on 76P

  • Several pieces of evidence indicate that h76p is involved in microtubule nucleation [1].
  • (1) h76p is localized at the centrosome as demonstrated by immunofluorescence [1].
  • (5) h76p is necessary for aster nucleation by sperm basal bodies and recombinant h76p partially replaces endogenous 76p in oocyte extracts [1].
  • We identified three genes, gfh1+, mod21+, and mod22+, in a screen for fission yeast mutants affecting microtubule organization. gfh1+ is a previously characterized gamma-TuC protein weakly similar to human gamma-TuC subunit GCP4, whereas mod21+ is novel and shows weak similarity to human gamma-TuC subunit GCP5 [2].

References

  1. Human 76p: A new member of the gamma-tubulin-associated protein family. Fava, F., Raynaud-Messina, B., Leung-Tack, J., Mazzolini, L., Li, M., Guillemot, J.C., Cachot, D., Tollon, Y., Ferrara, P., Wright, M. J. Cell Biol. (1999) [Pubmed]
  2. Noncore Components of the Fission Yeast {gamma}-Tubulin Complex. Anders, A., Louren??o, P.C., Sawin, K.E. Mol. Biol. Cell (2006) [Pubmed]
 
WikiGenes - Universities