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Gene Review

SCO4926  -  propionyl-CoA carboxylase complex B subunit

Streptomyces coelicolor A3(2)

Synonyms: SCK13.18c, pccB
 
 
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Disease relevance of SCO4926

  • A derivative of BAP1 was engineered that harbors the AHBA biosynthetic operon, the bicistronic RifA construct and the pccB and accA1 genes from Streptomyces coelicolor, which enable methylmalonyl-CoA biosynthesis [1].
 

High impact information on SCO4926

References

  1. Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli. Watanabe, K., Rude, M.A., Walsh, C.T., Khosla, C. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  2. Genetic and biochemical characterization of the alpha and beta components of a propionyl-CoA carboxylase complex of Streptomyces coelicolor A3(2). Rodríguez, E., Gramajo, H. Microbiology (Reading, Engl.) (1999) [Pubmed]
 
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