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Gene Review

nifB  -  nitrogen fixation protein

Nostoc sp. PCC 7120

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Disease relevance of nifB

  • Comparison of the nifB 5'-flanking sequence with the nifH 5'-flanking sequence did not reveal any consensus base pairs that would define a nif promoter for Anabaena [1].

High impact information on nifB

  • It is located just upstream of the nifHDK operon and consists of four genes in the order nifB, fdxN, nifS, and nifU [1].
  • The operon contains two instances of 7-base pair directly repeated sequences: seven copies of the repeated sequence are found between the nifB and fdxN genes and six copies are found between the nifS and nifU genes [1].
  • The nucleotide sequence of a region located downstream of the nifB gene, both in the cyanobacterium Anabaena sp. strain PCC 7120 and in Rhizobium meliloti, has been determined [2].

Biological context of nifB

  • The promoter for the nifB operon was located by primer extension [1].


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