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Gene Review

nifU  -  nitrogen fixation protein

Nostoc sp. PCC 7120

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Disease relevance of nifU

  • The nifU-nifH intergenic region of Nostoc sp. strain MUN 8820 was sequenced (1,229 bp) and was approximately 95% identical to the equivalent region in N. commune UTEX 584 [1].
  • Cloning of nifHD from Nostoc commune UTEX 584 and of a flanking region homologous to part of the Azotobacter vinelandii nifU gene [2].

High impact information on nifU

  • It is located just upstream of the nifHDK operon and consists of four genes in the order nifB, fdxN, nifS, and nifU [3].
  • The nucleotide sequence of the 3' end of the nifU coding sequence, the complete coding sequence of nifH and a substantial part of the 5' end of nifD coding sequence from Nostoc 6720 is presented [4].
  • Nitrogen-fixation by two species of Nostoc, one of them a lichen phycobiont, was generally stimulated by low concentrations of arsenic, cadmium, nickel, lead, palladium, and zinc [5].

Biological context of nifU


Other interactions of nifU

  • Each strand of the DNA from the nifU-nifH intergenic regions of both strains has the potential to fold into secondary structures in which more than 50% of the bases are internally paired [1].


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