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Gene Review:

hetP - similar to heterocyst formation protein HetP

Nostoc sp. PCC 7120

Fernández-Piñas, F. et al., Leganés, F. et al., Khudyakov, I. et al.

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Disease relevance of hetP

Analysis by pulsed-field gel electrophoresis localized the transposition at ca. 3.44 Mb on the physical map of the chromosome of wild-type Anabaena sp. The transposon was situated within an open reading frame (ORF), which we denote hetP, whose wild-type form was cloned and also sequenced [1].
Nostoc ellipsosporum possesses single copies of genes that hybridize with hetR and hetP [2].

High impact information on hetP

In contrast to the hetR mutant, a hetP mutant of N. ellipsosporum could form akinetes, but heterocyst formation was blocked [2].
Its N-terminal third is unique and does not resemble any known protein. hetC lies 1,165 bp 5' from the previously described gene hetP [3].

References

A third genetic locus required for the formation of heterocysts in Anabaena sp. strain PCC 7120. Fernández-Piñas, F., Leganés, F., Wolk, C.P. J. Bacteriol. (1994) [Pubmed]
Two mutations that block heterocyst differentiation have different effects on akinete differentiation in Nostoc ellipsosporum. Leganés, F., Fernández-Piñas, F., Wolk, C.P. Mol. Microbiol. (1994) [Pubmed]
hetC, a gene coding for a protein similar to bacterial ABC protein exporters, is involved in early regulation of heterocyst differentiation in Anabaena sp. strain PCC 7120. Khudyakov, I., Wolk, C.P. J. Bacteriol. (1997) [Pubmed]

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