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Idd11  -  insulin dependent diabetes susceptibility 11

Mus musculus

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High impact information on Idd11


Biological context of Idd11

  • We previously located a NOD diabetes susceptibility locus, designated Idd11, on mouse Chromosome (Chr) 4 by analyzing diabetic backcross mice produced after crossing NOD/Lt with the nondiabetic resistant strain C57BL/6 (B6) strain [3].


  1. Congenic nonobese diabetic mouse strains fail to confirm linkage of a marginal zone B lymphocyte phenotype to the Idd11 locus on chromosome 4. Brodnicki, T.C., O'Donnell, K., Quirk, F., Tarlinton, D.M. J. Immunol. (2006) [Pubmed]
  2. The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11. Rolf, J., Motta, V., Duarte, N., Lundholm, M., Berntman, E., Bergman, M.L., Sorokin, L., Cardell, S.L., Holmberg, D. J. Immunol. (2005) [Pubmed]
  3. Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene. Brodnicki, T.C., McClive, P., Couper, S., Morahan, G. Immunogenetics (2000) [Pubmed]
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