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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

DUSP12  -  dual specificity phosphatase 12

Homo sapiens

Synonyms: DUSP1, Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1, YVH1
 
 
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Disease relevance of DUSP12

  • CONCLUSION: ATF6 and DUSP12 seem to be the most likely candidate target genes for the 1q23 amplification in sarcomas [1].
 

High impact information on DUSP12

References

  1. Mapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGH. Kresse, S.H., Berner, J.M., Meza-Zepeda, L.A., Gregory, S.G., Kuo, W.L., Gray, J.W., Forus, A., Myklebost, O. Mol. Cancer (2005) [Pubmed]
  2. Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes. Das, S.K., Chu, W.S., Hale, T.C., Wang, X., Craig, R.L., Wang, H., Shuldiner, A.R., Froguel, P., Deloukas, P., McCarthy, M.I., Zeggini, E., Hasstedt, S.J., Elbein, S.C. Diabetes (2006) [Pubmed]
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