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Gene Review:

ODF3 - outer dense fiber of sperm tails 3

Homo sapiens

Synonyms: CT135, Outer dense fiber of sperm tails protein 3, Outer dense fiber protein 3, SHIPPO1, Sperm tail protein SHIPPO 1, ...

Egydio de Carvalho, C. et al.

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High impact information on ODF3

Molecular cloning and characterization of a complementary DNA encoding sperm tail protein SHIPPO 1 [1].
The amino acid sequence includes 6 Pro-Gly-Pro repeats, which are also present in the human orthologue protein (hSHIPPO 1) as well as in 2 other newly reported proteins of Drosophila melanogaster [1].

Anatomical context of ODF3

SHIPPO 1 in sperm is resistant to treatment with nonionic detergents and coextracted with the cytoskeletal core proteins of the mouse sperm tail [1].

Analytical, diagnostic and therapeutic context of ODF3

Antibody raised against SHIPPO 1 identified a testis-specific M(r) 32 x 10(-3) band in Western blot analysis [1].

References

Molecular cloning and characterization of a complementary DNA encoding sperm tail protein SHIPPO 1. Egydio de Carvalho, C., Tanaka, H., Iguchi, N., Ventelä, S., Nojima, H., Nishimune, Y. Biol. Reprod. (2002) [Pubmed]

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