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Gene Review

Ubqln1  -  ubiquilin 1

Rattus norvegicus

Synonyms: Da41, PLIC-1, Plic1, Protein linking IAP with cytoskeleton 1, Ubiquilin-1
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High impact information on Ubqln1

  • Furthermore, Plic-1 is enriched at inhibitory synapses and is associated with subsynaptic membranes [1].
  • Plic-1 also enhances the stability of intracellular GABA(A) receptor subunits, increasing the number of receptors available for insertion into the plasma membrane [1].


  1. GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1. Bedford, F.K., Kittler, J.T., Muller, E., Thomas, P., Uren, J.M., Merlo, D., Wisden, W., Triller, A., Smart, T.G., Moss, S.J. Nat. Neurosci. (2001) [Pubmed]
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