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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TUBGCP5  -  tubulin, gamma complex associated protein 5

Homo sapiens

Synonyms: GCP-5, GCP5, Gamma-tubulin complex component 5, KIAA1899
 
 
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High impact information on TUBGCP5

  • We identified three genes, gfh1+, mod21+, and mod22+, in a screen for fission yeast mutants affecting microtubule organization. gfh1+ is a previously characterized gamma-TuC protein weakly similar to human gamma-TuC subunit GCP4, whereas mod21+ is novel and shows weak similarity to human gamma-TuC subunit GCP5 [1].
  • GCP5 and GCP6: two new members of the human gamma-tubulin complex [2].
 

Anatomical context of TUBGCP5

  • GCP5 and GCP6, like other components of the gamma-tubulin complex, localize to the centrosome and associate with microtubules, suggesting that the entire gamma-tubulin complex takes part in both of these interactions [2].

References

  1. Noncore Components of the Fission Yeast {gamma}-Tubulin Complex. Anders, A., Louren??o, P.C., Sawin, K.E. Mol. Biol. Cell (2006) [Pubmed]
  2. GCP5 and GCP6: two new members of the human gamma-tubulin complex. Murphy, S.M., Preble, A.M., Patel, U.K., O'Connell, K.L., Dias, D.P., Moritz, M., Agard, D., Stults, J.T., Stearns, T. Mol. Biol. Cell (2001) [Pubmed]
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