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Gene Review

SLC25A26  -  solute carrier family 25 (S...

Homo sapiens

Synonyms: Mitochondrial S-adenosylmethionine transporter, S-adenosylmethionine mitochondrial carrier protein, SAMC, Solute carrier family 25 member 26
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High impact information on SLC25A26

  • The physiological role of SAMC is probably to exchange cytosolic SAM for mitochondrial S-adenosylhomocysteine [1].
  • SAMC was found to be expressed in all human tissues examined and was localized to the mitochondria [1].
  • Unlike the yeast orthologue, SAMC catalysed virtually only countertransport, exhibited a higher transport affinity for SAM and was strongly inhibited by tannic acid and Bromocresol Purple [1].


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