Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

CNTROB - centrobin, centrosomal BRCA2 interacting...

Homo sapiens

Synonyms: Centrobin, Centrosomal BRCA2-interacting protein, LIP8, LYST-interacting protein 8, PP1221

Zou, C. et al.

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High impact information on CNTROB

Furthermore, inhibition of centriole duplication by centrobin depletion led to impaired cytokinesis [1].
The silencing of centrobin expression by small interfering RNA inhibited centriole duplication and resulted in centrosomes with one or no centriole, demonstrating that centrobin is required for centriole duplication [1].

Anatomical context of CNTROB

Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication [1].

References

Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication. Zou, C., Li, J., Bai, Y., Gunning, W.T., Wazer, D.E., Band, V., Gao, Q. J. Cell Biol. (2005) [Pubmed]

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