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Ppp2r1a  -  protein phosphatase 2, regulatory subunit...

Rattus norvegicus

 
 
 
 
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High impact information on Ppp2r1a

  • PR65 alpha overexpressing rat embryo fibroblasts (REF-52 cells) become multinucleated [1].
  • Deletion of the 5'-UTR allows efficient translation of the PR65 alpha message in vitro and overexpression in COS-1 cells [1].

References

  1. Deregulation of translational control of the 65-kDa regulatory subunit (PR65 alpha) of protein phosphatase 2A leads to multinucleated cells. Wera, S., Fernandez, A., Lamb, N.J., Turowski, P., Hemmings-Mieszczak, M., Mayer-Jaekel, R.E., Hemmings, B.A. J. Biol. Chem. (1995) [Pubmed]
 
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