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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Gpi1  -  CG32578 gene product from transcript...

Drosophila melanogaster

Synonyms: CG32578, Dm_CAC10056/216-441, Dmel\CG32578, dGpi1, i19e, ...
 
 
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High impact information on Gpi1

  • The molecular evolution of nonA and dGpi1 sequences show remarkable differences, with the latter revealing a level of amino acid divergence that is as high as that of transformer and with extremely low levels of codon bias [1].
  • This gene encodes a protein that shows similarities to GPI1, which is required for the biosynthesis of glycosylphosphatidylinositol (GPI), a component for anchoring eukaryotic proteins to membranes, and so we have named it dGpi1 [1].
  • Molecular Dissection of the 5' Region of no-on-transientA of Drosophila melanogaster Reveals cis-Regulation by Adjacent dGpi1 Sequences [2].
  • Full rescue of nonA mutant phenotypes can be achieved by transformation with a genomic clone that carries approximately 2 kb of 5' regulatory material and that encodes most of the coding sequence of dGpi1 [2].

References

  1. Comparative analysis of the nonA region in Drosophila identifies a highly diverged 5' gene that may constrain nonA promoter evolution. Campesan, S., Chalmers, D., Sandrelli, F., Megighian, A., Peixoto, A.A., Costa, R., Kyriacou, C.P. Genetics (2001) [Pubmed]
  2. Molecular Dissection of the 5' Region of no-on-transientA of Drosophila melanogaster Reveals cis-Regulation by Adjacent dGpi1 Sequences. Sandrelli, F., Campesan, S., Rossetto, M., Benna, C., Zieger, E., Megighian, A., Couchman, M., Kyriacou, C., Costa, R. Genetics (2001) [Pubmed]
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