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Gene Review:

rep - rep

Pseudomonas putida

Krasowiak, R. et al., Shintani, M. et al.

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Disease relevance of rep

The minimal replicon from IncP-9 plasmid pM3, consisting of oriV and rep, is able to replicate in Pseudomonas putida but not in Escherichia coli, unless production of Rep protein is increased [1].

High impact information on rep

Characterization of the Replication, Maintenance, and Transfer Features of the IncP-7 Plasmid pCAR1, Which Carries Genes Involved in Carbazole and Dioxin Degradation [2].
The block closest to rep is not necessary for oriV function [1].

References

IncP-9 replication initiator protein binds to multiple DNA sequences in oriV and recruits host DnaA protein. Krasowiak, R., Sevastsyanovich, Y., Konieczny, I., Bingle, L.E., Thomas, C.M. Plasmid (2006) [Pubmed]
Characterization of the Replication, Maintenance, and Transfer Features of the IncP-7 Plasmid pCAR1, Which Carries Genes Involved in Carbazole and Dioxin Degradation. Shintani, M., Yano, H., Habe, H., Omori, T., Yamane, H., Tsuda, M., Nojiri, H. Appl. Environ. Microbiol. (2006) [Pubmed]

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