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Gene Review

sopE2  -  guanine nucleotide exchange factor sopE2

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

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Disease relevance of sopE2

  • We found that sipA, sopE, and, to a lesser degree, sopE2 contribute to murine colitis, but we could not assign an inflammation phenotype to sopB [1].
  • SopE, which is 70% identical to sopE2 is only present in some Salmonella strains and emerged later well after the divergence of the contemporary Salmonella lineages [2].

High impact information on sopE2


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